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Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21
Modification of proteins by ubiquitin (Ub) and Ub-like (Ubl) modifiers regulates a variety of cellular functions. The ability of Ub to form chains of eight structurally and functionally distinct types adds further complexity to the system. Ub-specific proteases (USPs) hydrolyse polyUb chains, and so...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077245/ https://ncbi.nlm.nih.gov/pubmed/21399617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.17 |
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