JAM-A regulates epithelial proliferation through Akt/β-catenin signalling

Expression of the tight junction protein junctional adhesion molecule-A (JAM-A) has been linked to proliferation and tumour progression. However, a direct role for JAM-A in regulating proliferative processes has not been shown. By using complementary in vivo and in vitro approaches, we demonstrate t...

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Detalhes bibliográficos
Main Authors: Nava, Porfirio, Capaldo, Christopher T, Koch, Stefan, Kolegraff, Keli, Rankin, Carl Robert, Farkas, Attila E, Feasel, Mattie E, Li, Linheng, Addis, Caroline, Parkos, Charles A, Nusrat, Asma
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077244/
https://ncbi.nlm.nih.gov/pubmed/21372850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.16
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