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A New Trick (Hydroxyl Radical Generation) For An Old Vitamin (B(12))
[Image: see text] Photolysis of hydroxocobalamin in the presence of plasmid DNA (pBR322) results in DNA cleavage. Temporal control of hydroxyl radical production and DNA strand scission by hydroxocobalamin was demonstrated using a 2-deoxyribose assay and a plasmid relaxation assay, respectively. The...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077068/ https://ncbi.nlm.nih.gov/pubmed/21275391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111585c |
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