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Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

Caspase-1 plays a key role in inflammatory pathways by processing pro-IL-1β into the active cytokine mature IL-1β. Given its sequence similarity with the Caenorhabditis elegans cell death gene ced-3,it has long been speculated that caspase-1 may also play a role in cell death. However, an unequivoca...

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Hlavní autoři: Zhang, Wen-Hua, Wang, Xin, Narayanan, Malini, Zhang, Yu, Huo, Chunfeng, Reed, John C., Friedlander, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC307684/
https://ncbi.nlm.nih.gov/pubmed/14663141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534856100
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