Dysregulation of Receptor Interacting Protein-2 and Caspase Recruitment Domain Only Protein Mediates Aberrant Caspase-1 Activation in Huntington's Disease

Caspase-1 plays a role in the pathogenesis of a variety of neurological diseases. Caspase-1 activation is an early event in models of Huntington's disease (HD). However, mechanisms regulating the activation of this apical caspase in cell death are not known. Receptor interacting protein-2 (Rip2...

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Publicat a:J Neurosci
Autors principals: Wang, Xin, Wang, Hongyan, Figueroa, Bryan E., Zhang, Wen-hua, Huo, Chunfeng, Guan, Yingjun, Zhang, Yu, Bruey, Jean-Marie, Reed, John C., Friedlander, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726023/
https://ncbi.nlm.nih.gov/pubmed/16354923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4181-05.2005
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