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Tidal surge in the M2 proton channel, sensed by 2D IR spectroscopy

The M2 proton channel from influenza A virus transmits protons across membranes via a narrow aqueous pore lined by water and a proton sensor, His37. Near the center of the membrane, a water cluster is stabilized by the carbonyl of Gly34 and His37, the properties of which are modulated by protonation...

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Detalhes bibliográficos
Main Authors: Ghosh, Ayanjeet, Qiu, Jade, DeGrado, William F., Hochstrasser, Robin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076828/
https://ncbi.nlm.nih.gov/pubmed/21444789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103027108
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