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LRP-1 variation is not associated with risk of Alzheimer's disease

Alzheimer's disease (AD) is characterised by the extensive deposition of amyloid beta (Aβ) within the parenchyma and vasculature of the brain. It is hypothesised that a dysfunction in Aβ degradation and/or its removal from the brain may result in accumulation as plaques. Low density lipoprotein...

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Autors principals: Chalmers, Katy A, Barker, Rachel, Passmore, Peter A, Panza, Francesco, Seripa, Davide, Solfrizzi, Vincenzo, Love, Seth, Prince, Jonathan A, Kehoe, Patrick G
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076756/
https://ncbi.nlm.nih.gov/pubmed/21537384
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