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Activators and inhibitors of the plasminogen system in Alzheimer’s disease

Accumulation and deposition of Aβ is one of the main neuropathological hallmarks of Alzheimer’s disease (AD) and impaired Aβ degradation may be one mechanism of accumulation. Plasmin is the key protease of the plasminogen system and can cleave Aβ. Plasmin is activated from plasminogen by tissue plas...

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Main Authors: Barker, Rachel, Kehoe, Patrick G, Love, Seth
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822855/
https://ncbi.nlm.nih.gov/pubmed/21790972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01394.x
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