Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis

For late onset Alzheimer's disease (LOAD), the only confirmed, genetic association is with the apolipoprotein E (APOE) locus on chromosome 19. Meta-analysis is often employed to sort the true associations from the false positives. LOAD research has the advantage of a continuously updated meta-a...

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Main Authors: Webster, Jennifer, Reiman, Eric M, Zismann, Victoria L, Joshipura, Keta D, Pearson, John v, Hu-Lince, Diane, Huentelman, Matthew J, Craig, David W, Coon, Keith D, Beach, Thomas, Rohrer, Kristen C, Zhao, Alice S, Leung, Doris, Bryden, Leslie, Marlowe, Lauren, Kaleem, Mona, Mastroeni, Diego, Grover, Andrew, Rogers, Joseph, Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Heward, Christopher B, Ravid, Rivka, Hutton, Michael L, Melquist, Stacey, Petersen, Ron C, Caselli, Richard J, Papassotiropoulos, Andreas, Stephan, Dietrich A, Hardy, John, Myers, Amanda
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2009
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076748/
https://ncbi.nlm.nih.gov/pubmed/21537449
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