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Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex with other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inact...

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Detalhes bibliográficos
Main Authors: Wolfman, Neil M., McPherron, Alexandra C., Pappano, William N., Davies, Monique V., Song, Kening, Tomkinson, Kathleen N., Wright, Jill F., Zhao, Liz, Sebald, Suzanne M., Greenspan, Daniel S., Lee, Se-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307655/
https://ncbi.nlm.nih.gov/pubmed/14671324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534946100
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