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Suppression of body fat accumulation in myostatin-deficient mice

Myostatin is a TGF-β family member that acts as a negative regulator of muscle growth. Mice lacking the myostatin gene (Mstn) have a widespread increase in skeletal muscle mass resulting from a combination of muscle fiber hypertrophy and hyperplasia. Here we show that Mstn-null mice have a significa...

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Detalhes bibliográficos
Main Authors: McPherron, Alexandra C., Lee, Se-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150888/
https://ncbi.nlm.nih.gov/pubmed/11877467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13562
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