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Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex with other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inact...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307655/ https://ncbi.nlm.nih.gov/pubmed/14671324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534946100 |
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