Induction of colitis by a CD4(+) T cell clone specific for a bacterial epitope

It is now well established that the intestinal flora plays an important role in the pathogenesis of inflammatory bowel disease (IBD). However, whether bacteria serve as the sole target of the immune response in this process or whether they act indirectly by triggering an anti-self response is still...

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Detalles Bibliográficos
Autores principales: Kullberg, Marika C., Andersen, John F., Gorelick, Peter L., Caspar, Patricia, Suerbaum, Sebastian, Fox, James G., Cheever, Allen W., Jankovic, Dragana, Sher, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC307653/
https://ncbi.nlm.nih.gov/pubmed/14673119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534546100
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