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Induction of colitis by a CD4(+) T cell clone specific for a bacterial epitope

It is now well established that the intestinal flora plays an important role in the pathogenesis of inflammatory bowel disease (IBD). However, whether bacteria serve as the sole target of the immune response in this process or whether they act indirectly by triggering an anti-self response is still...

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Detalhes bibliográficos
Main Authors: Kullberg, Marika C., Andersen, John F., Gorelick, Peter L., Caspar, Patricia, Suerbaum, Sebastian, Fox, James G., Cheever, Allen W., Jankovic, Dragana, Sher, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307653/
https://ncbi.nlm.nih.gov/pubmed/14673119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534546100
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