Induction of colitis by a CD4(+) T cell clone specific for a bacterial epitope

It is now well established that the intestinal flora plays an important role in the pathogenesis of inflammatory bowel disease (IBD). However, whether bacteria serve as the sole target of the immune response in this process or whether they act indirectly by triggering an anti-self response is still...

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Bibliographic Details
Main Authors: Kullberg, Marika C., Andersen, John F., Gorelick, Peter L., Caspar, Patricia, Suerbaum, Sebastian, Fox, James G., Cheever, Allen W., Jankovic, Dragana, Sher, Alan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307653/
https://ncbi.nlm.nih.gov/pubmed/14673119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2534546100
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