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Current issues with acetaminophen hepatotoxicity–a clinically relevant model to test the efficacy of natural products

There is a significant need to evaluate the therapeutic potential of natural products and other compounds purported to be hepatoprotective. Acetaminophen-induced liver injury, especially in mice, is an attractive and widely used model for this purpose because it is both clinically relevant and exper...

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Bibliografiske detaljer
Main Authors: Jaeschke, Hartmut, McGill, Mitchell R., Williams, C. David, Ramachandran, Anup
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076526/
https://ncbi.nlm.nih.gov/pubmed/21296090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.01.025
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