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Antigen-driven effector CD8 T cell function regulated by T-bet

Type 1 immunity relies on the differentiation of two major subsets of T lymphocytes, the CD4(+) T helper (Th) cell and the CD8(+) cytotoxic T cell, that direct inflammatory and cytotoxic responses essential for the destruction of intracellular and extracellular pathogens. In contrast to CD4 cells, l...

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Détails bibliographiques
Auteurs principaux: Sullivan, Brandon M., Juedes, Amy, Szabo, Susanne J., von Herrath, Matthias, Glimcher, Laurie H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC307651/
https://ncbi.nlm.nih.gov/pubmed/14673093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2636938100
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