Increased Memory Conversion of Naïve CD8 T Cells Activated during Late Phases of Acute Virus Infection Due to Decreased Cumulative Antigen Exposure

BACKGROUND: Memory CD8 T cells form an essential part of protective immunity against viral infections. Antigenic load, costimulation, CD4-help, cytokines and chemokines fluctuate during the course of an antiviral immune response thus affecting CD8 T cell activation and memory conversion. METHODOLOGY...

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Detalhes bibliográficos
Main Authors: Fousteri, Georgia, Dave, Amy, Juedes, Amy, Juntti, Therese, Morin, Bret, Togher, Lisa, Farber, Donna L., von Herrath, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017078/
https://ncbi.nlm.nih.gov/pubmed/21253594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014502
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