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Mechanics of the IL2RA Gene Activation Revealed by Modeling and Atomic Force Microscopy
Transcription implies recruitment of RNA polymerase II and transcription factors (TFs) by DNA melting near transcription start site (TSS). Combining atomic force microscopy and computer modeling, we investigate the structural and dynamical properties of the IL2RA promoter and identify an intrinsical...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076448/ https://ncbi.nlm.nih.gov/pubmed/21533205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018811 |
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