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The Rostral Migratory Stream Plays a Key Role in Intranasal Delivery of Drugs into the CNS

BACKGROUND: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into the CNS. So far, the anatomical s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scranton, Robert A., Fletcher, Lauren, Sprague, Shane, Jimenez, David F., Digicaylioglu, Murat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076435/
https://ncbi.nlm.nih.gov/pubmed/21533252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018711
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