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The Rostral Migratory Stream Plays a Key Role in Intranasal Delivery of Drugs into the CNS

BACKGROUND: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into the CNS. So far, the anatomical s...

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Detalhes bibliográficos
Main Authors: Scranton, Robert A., Fletcher, Lauren, Sprague, Shane, Jimenez, David F., Digicaylioglu, Murat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076435/
https://ncbi.nlm.nih.gov/pubmed/21533252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018711
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