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The Rostral Migratory Stream Plays a Key Role in Intranasal Delivery of Drugs into the CNS

BACKGROUND: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into the CNS. So far, the anatomical s...

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Bibliografiske detaljer
Main Authors: Scranton, Robert A., Fletcher, Lauren, Sprague, Shane, Jimenez, David F., Digicaylioglu, Murat
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076435/
https://ncbi.nlm.nih.gov/pubmed/21533252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018711
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