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Innate immunity and PBC: Activated invariant NKT cells exacerbate murine autoimmune cholangitis and fibrosis

Murine models of autoimmunity allow the study of the earliest events in disease pathogenesis. Our laboratory has developed a xenobiotic induced model of primary biliary cirrhosis (PBC) following immunization of mice with 2-octynoic acid coupled to bovine serum albumin (2-OA-BSA), an antigen selected...

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Detalhes bibliográficos
Main Authors: Wu, Si-Jie, Yang, Yao-Hsu, Tsuneyama, Koichi, Leung, Patrick S.C., Illarionov, Petr, Gershwin, M. Eric, Chuang, Ya-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076334/
https://ncbi.nlm.nih.gov/pubmed/21374662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24113
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