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Controlling pH in shake flasks using polymer-based controlled-release discs with pre-determined release kinetics

BACKGROUND: There are significant differences in the culture conditions between small-scale screenings and large-scale fermentation processes. Production processes are usually conducted in fed-batch cultivation mode with active pH-monitoring and control. In contrast, screening experiments in shake f...

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Détails bibliographiques
Auteurs principaux: Scheidle, Marco, Dittrich, Barbara, Klinger, Johannes, Ikeda, Hideo, Klee, Doris, Büchs, Jochen
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076237/
https://ncbi.nlm.nih.gov/pubmed/21429210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-25
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