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Making Sense of Nonsense GABA(A) Receptor Mutations Associated with Genetic Epilepsies

Nonsense mutations that generate premature translation-termination codons (PTCs) are responsible for about one-third of human genetic diseases. PTCs in both voltage- and ligand-gated ion channel genes, including sodium, potassium, nicotinic cholinergic receptor and GABA(A) receptor channel genes hav...

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Detalhes bibliográficos
Main Authors: Kang, Jing-Qiong, Macdonald, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076198/
https://ncbi.nlm.nih.gov/pubmed/19717338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2009.07.003
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