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Targeting Protein Tyrosine Phosphatases for Anticancer Drug Discovery

Protein tyrosine phosphatases (PTPs) are a diverse family of enzymes encoded by 107 genes in the human genome. Together with protein tyrosine kinases (PTKs), PTPs regulate various cellular activities essential for the initiation and maintenance of malignant phenotypes. While PTK inhibitors are now u...

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Autors principals: Scott, Latanya. M., Lawrence, Harshani. R., Sebti, Saïd. M., Lawrence, Nicholas. J., Wu, Jie.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076191/
https://ncbi.nlm.nih.gov/pubmed/20337577
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