Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

Protein tyrosine phosphatases are often exploited and subverted by pathogenic bacteria to cause human diseases. The tyrosine phosphatase mPTPB from Mycobacterium tuberculosis is an essential virulence factor that is secreted by the bacterium into the cytoplasm of macrophages, where it mediates mycob...

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Detalhes bibliográficos
Main Authors: Zhou, Bo, He, Yantao, Zhang, Xian, Xu, Jie, Luo, Yong, Wang, Yuehong, Franzblau, Scott G., Yang, Zhenyun, Chan, Rebecca J., Liu, Yan, Zheng, Jianyu, Zhang, Zhong-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842023/
https://ncbi.nlm.nih.gov/pubmed/20167798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909133107
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