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Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

Protein tyrosine phosphatases are often exploited and subverted by pathogenic bacteria to cause human diseases. The tyrosine phosphatase mPTPB from Mycobacterium tuberculosis is an essential virulence factor that is secreted by the bacterium into the cytoplasm of macrophages, where it mediates mycob...

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Autori principali: Zhou, Bo, He, Yantao, Zhang, Xian, Xu, Jie, Luo, Yong, Wang, Yuehong, Franzblau, Scott G., Yang, Zhenyun, Chan, Rebecca J., Liu, Yan, Zheng, Jianyu, Zhang, Zhong-Yin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842023/
https://ncbi.nlm.nih.gov/pubmed/20167798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909133107
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