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Inhibition of 5α-Reductase Enhances Testosterone-Induced Expression of U19/Eaf2 Tumor Suppressor During the Regrowth of LNCaP Xenograft Tumor in Nude Mice

BACKGROUND: Intermittent androgen deprivation therapy (IADT) was developed to improve the quality of life and retard prostate cancer progression to castration resistance. IADT involves regrowth of the tumor during the off cycle upon testosterone recovery. Our previous studies showed that testosteron...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Shubham, Wang, Yujuan, Ramos-Garcia, Raquel, Shevrin, Daniel, Nelson, Joel B, Wang, Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076187/
https://ncbi.nlm.nih.gov/pubmed/20564326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21193
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