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Inhibition of 5α-Reductase Enhances Testosterone-Induced Expression of U19/Eaf2 Tumor Suppressor During the Regrowth of LNCaP Xenograft Tumor in Nude Mice

BACKGROUND: Intermittent androgen deprivation therapy (IADT) was developed to improve the quality of life and retard prostate cancer progression to castration resistance. IADT involves regrowth of the tumor during the off cycle upon testosterone recovery. Our previous studies showed that testosteron...

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Detalhes bibliográficos
Main Authors: Gupta, Shubham, Wang, Yujuan, Ramos-Garcia, Raquel, Shevrin, Daniel, Nelson, Joel B, Wang, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076187/
https://ncbi.nlm.nih.gov/pubmed/20564326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21193
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