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Inhibition of 5α-Reductase Enhances Testosterone-Induced Expression of U19/Eaf2 Tumor Suppressor During the Regrowth of LNCaP Xenograft Tumor in Nude Mice
BACKGROUND: Intermittent androgen deprivation therapy (IADT) was developed to improve the quality of life and retard prostate cancer progression to castration resistance. IADT involves regrowth of the tumor during the off cycle upon testosterone recovery. Our previous studies showed that testosteron...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076187/ https://ncbi.nlm.nih.gov/pubmed/20564326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21193 |
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