5α-reductase Inhibition Coupled with Short Off Cycles Increases Survival in the LNCaP Xenograft Prostate Tumor Model on Intermittent Androgen Deprivation Therapy

PURPOSE: Intermittent androgen deprivation therapy (IADT) for patients with PSA progression after treatment for localized prostate cancer is an alternative to the standard continuous ADT. IADT allows for the recovery of testosterone during off-cycles to stimulate regrowth and differentiation of the...

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Detalhes bibliográficos
Publicado no:J Urol
Main Authors: Pascal, Laura E., Masoodi, Khalid Z., O’Malley, Katherine J., Shevrin, Daniel, Gingrich, Jeffrey R., Parikh, Rahul A., Wang, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404193/
https://ncbi.nlm.nih.gov/pubmed/25444984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2014.10.101
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