5α-reductase Inhibition Coupled with Short Off Cycles Increases Survival in the LNCaP Xenograft Prostate Tumor Model on Intermittent Androgen Deprivation Therapy

PURPOSE: Intermittent androgen deprivation therapy (IADT) for patients with PSA progression after treatment for localized prostate cancer is an alternative to the standard continuous ADT. IADT allows for the recovery of testosterone during off-cycles to stimulate regrowth and differentiation of the...

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Vydáno v:J Urol
Hlavní autoři: Pascal, Laura E., Masoodi, Khalid Z., O’Malley, Katherine J., Shevrin, Daniel, Gingrich, Jeffrey R., Parikh, Rahul A., Wang, Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404193/
https://ncbi.nlm.nih.gov/pubmed/25444984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2014.10.101
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