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Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy
The hyperglycemia of maternal diabetes suppresses the glucose transporter-1 (GLUT1) facilitative glucose transporter 49–66% in preimplantation embryos. Glucose uptake is reduced and apoptosis is activated. We hypothesized that the reduction of embryonic GLUT1 may play a key role in the malformations...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307616/ https://ncbi.nlm.nih.gov/pubmed/14673082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536196100 |
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