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Processive Replication of Single DNA Molecules in a Nanopore Catalyzed by phi29 DNA Polymerase
Coupling nucleic acid processing enzymes to nanoscale pores allows controlled movement of individual DNA or RNA strands that is reported as an ionic current time series. Hundreds of individual enzyme complexes can be examined in single-file order at high bandwidth and spatial resolution. The bacteri...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076064/ https://ncbi.nlm.nih.gov/pubmed/21121604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1087612 |
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