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Processive Replication of Single DNA Molecules in a Nanopore Catalyzed by phi29 DNA Polymerase

Coupling nucleic acid processing enzymes to nanoscale pores allows controlled movement of individual DNA or RNA strands that is reported as an ionic current time series. Hundreds of individual enzyme complexes can be examined in single-file order at high bandwidth and spatial resolution. The bacteri...

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Bibliografiske detaljer
Main Authors: Lieberman, Kate R., Cherf, Gerald M., Doody, Michael J., Olasagasti, Felix, Kolodji, Yvette, Akeson, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076064/
https://ncbi.nlm.nih.gov/pubmed/21121604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1087612
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