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Mapping the Position of DNA Polymerase-Bound DNA Templates in a Nanopore at 5 Å Resolution

RP-45 DNA polymerases are molecular motors that catalyze template-dependent DNA replication, advancing along template DNA by one nucleotide with each catalytic cycle. Nanopore-based measurements have emerged as a single molecule technique for the study of these enzymes. Using the a-hemolysin nanopor...

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Detalhes bibliográficos
Main Authors: Gyarfas, B., Olasagasti, F., Benner, S., Garalde, D., Lieberman, K.R., Akeson, M., Walker, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Biomolecular Resource Facilities 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918045/
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