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Mapping the Position of DNA Polymerase-Bound DNA Templates in a Nanopore at 5 Å Resolution
RP-45 DNA polymerases are molecular motors that catalyze template-dependent DNA replication, advancing along template DNA by one nucleotide with each catalytic cycle. Nanopore-based measurements have emerged as a single molecule technique for the study of these enzymes. Using the a-hemolysin nanopor...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Association of Biomolecular Resource Facilities
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918045/ |
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