The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance

Emergence of chronic ‘sterile’ inflammation during obesity in absence of overt infection or autoimmune process is a puzzling phenomenon. The Nod Like Receptor (NLR) family of innate immune cell sensors like the Nlrp3 inflammasome are implicated in recognizing certain non-microbial origin ‘danger–sig...

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Bibliographic Details
Main Authors: Vandanmagsar, Bolormaa, Youm, Yun-Hee, Ravussin, Anthony, Galgani, Jose E., Stadler, Krisztian, Mynatt, Randall L., Ravussin, Eric, Stephens, Jacqueline M., Dixit, Vishwa Deep
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076025/
https://ncbi.nlm.nih.gov/pubmed/21217695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2279
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