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Genetic Ablation of Sfrp4 in Mice Does Not Affect Serum Phosphate Homeostasis

Serum phosphate levels are regulated by PTH and the fibroblast growth factor 23 (Fgf23)/Klotho endocrine system, which both affect expression of Npt2a and thus the apical reabsorption of phosphate in the proximal renal tubules. In addition to Fgf23, secreted frizzled-related protein 4 (Sfrp4) has re...

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主要な著者: Christov, Marta, Koren, Shany, Yuan, Quan, Baron, Roland, Lanske, Beate
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075942/
https://ncbi.nlm.nih.gov/pubmed/21427221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1351
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