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Conformations and dynamics of Ets-1 ETS domain–DNA complexes

Molecular dynamics studies have been performed for 3.5 ns on the ETS domain of Ets-1 transcription factor bound to the 14-bp DNA, d(AGTGCCGGAAATGT), comprising the core sequence of high-affinity (GGAA), ETS–GGAA. In like manner, molecular dynamics simulations have been carried out for 3.9 ns on the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reddy, Swarnalatha Y., Obika, Satoshi, Bruice, Thomas C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307592/
https://ncbi.nlm.nih.gov/pubmed/14673097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1936251100
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