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Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo
Meningiomas are the most commonly occurring intracranial tumors and account for approximately 15−20% of central nervous system tumors. Patients whose tumors recur after surgery and radiation therapy have limited therapeutic options. It has also been reported recently that radiation triggers DNA repa...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075802/ https://ncbi.nlm.nih.gov/pubmed/21290090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.934 |
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