Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo

Meningiomas are the most commonly occurring intracranial tumors and account for approximately 15−20% of central nervous system tumors. Patients whose tumors recur after surgery and radiation therapy have limited therapeutic options. It has also been reported recently that radiation triggers DNA repa...

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Main Authors: Gupta, Reshu, Gogineni, Venkateswara Rao, Nalla, Arun Kumar, Chetty, Chandramu, Klopfenstein, Jeffrey D., Tsung, Andrew J., Mohanam, Sanjeeva, Rao, Jasti S.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075802/
https://ncbi.nlm.nih.gov/pubmed/21290090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.934
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