Oxidative Modifications of the C-terminal Domain of Tropoelastin Prevent Cell Binding

Tropoelastin (TE), the soluble monomer of elastin, is synthesized by elastogenic cells, such as chondrocytes, fibroblasts, and smooth muscle cells (SMCs). The C-terminal domain of TE interacts with cell receptors, and these interactions play critical roles in elastic fiber assembly. We recently foun...

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Autori principali: Akhtar, Kamal, Broekelmann, Thomas J., Song, Haowei, Turk, John, Brett, Tom J., Mecham, Robert P., Adair-Kirk, Tracy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075703/
https://ncbi.nlm.nih.gov/pubmed/21321118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192088
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