Oxidative and Nitrosative Modifications of Tropoelastin Prevent Elastic Fiber Assembly in Vitro

Elastic fibers are extracellular structures that provide stretch and recoil properties of tissues, such as lungs, arteries, and skin. Elastin is the predominant component of elastic fibers. Tropoelastin (TE), the precursor of elastin, is synthesized mainly during late fetal and early postnatal stage...

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Bibliografiske detaljer
Main Authors: Akhtar, Kamal, Broekelmann, Thomas J., Miao, Ming, Keeley, Fred W., Starcher, Barry C., Pierce, Richard A., Mecham, Robert P., Adair-Kirk, Tracy L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988345/
https://ncbi.nlm.nih.gov/pubmed/20847053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126789
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