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A Third Metal Is Required for Catalytic Activity of the Signal-transducing Protein Phosphatase M tPphA
Protein phosphatase M (PPM) regulates key signaling pathways in prokaryotes and eukaryotes. Novel structures of bacterial PPM members revealed three divalent metal ions in their catalytic centers. The function of metal 3 (M3) remained unclear. To reveal its function, we created variants of tPphA fro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075694/ https://ncbi.nlm.nih.gov/pubmed/21310952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036467 |
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