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Mechanistic and Structural Insights into the Regioselectivity of an Acyl-CoA Fatty Acid Desaturase via Directed Molecular Evolution

Membrane-bound fatty acid desaturases and related enzymes play a pivotal role in the biosynthesis of unsaturated and various unusual fatty acids. Structural insights into the remarkable catalytic diversity and wide range of substrate specificities of this class of enzymes remain limited due to the l...

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Detalhes bibliográficos
Main Authors: Vanhercke, Thomas, Shrestha, Pushkar, Green, Allan G., Singh, Surinder P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075633/
https://ncbi.nlm.nih.gov/pubmed/21300802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191098
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