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Caenorhabditis elegans Δ12-Desaturase FAT-2 Is a Bifunctional Desaturase Able to Desaturate a Diverse Range of Fatty Acid Substrates at the Δ12 and Δ15 Positions

Caenorhabditis elegans FAT-2 has been characterized as fatty acid Δ12-desaturase able to desaturate C16 and C18 fatty acids. However, in this report we show that when expressed in yeast cells this enzyme can also catalyze Δ15 desaturation. This results in the production of both linoleic acid (ω6 C18...

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Detalles Bibliográficos
Main Authors: Zhou, Xue-Rong, Green, Allan G., Singh, Surinder P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243535/
https://ncbi.nlm.nih.gov/pubmed/22041902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266114
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