A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans

BACKGROUND: Caenorhabditis elegans provides a genetically tractable model organism to investigate the network of genes involved in fat metabolism and how regulation is perturbed to produce the complex phenotype of obesity. C. elegans possess the full range of desaturases, including the Δ9 desaturase...

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Bibliographic Details
Main Authors: Castro, Cecilia, Sar, Funda, Shaw, W Robert, Mishima, Masanori, Miska, Eric A, Griffin, Julian L
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398271/
https://ncbi.nlm.nih.gov/pubmed/22264337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-36
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