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The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

In Parkinson's disease (PD), loss of striatal dopaminergic (DA) terminals and degeneration of DA neurons in the substantia nigra (SN) are associated with glial reactions. Such inflammatory processes are commonly considered an epiphenomenon of neuronal degeneration. However, there is increasing...

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Detalhes bibliográficos
Main Authors: Deleidi, Michela, Hallett, Penelope J., Koprich, James B., Chung, Chee-Yeun, Isacson, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075577/
https://ncbi.nlm.nih.gov/pubmed/21123556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2400-10.2010
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