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Variation in the ADH1B proximal promoter affects expression
The primary pathway of metabolism of dietary alcohol is via its oxidation in liver by alcohol dehydrogenases (ADH). Differences in the ADH enzyme activity or levels of enzyme present could affect the risk for alcoholism. Regulatory variations have been shown to affect the promoter activity and there...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075324/ https://ncbi.nlm.nih.gov/pubmed/21168396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.12.007 |
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