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Genetic Variation of the IL-28B Promoter Affecting Gene Expression

The current standard of care for the treatment of chronic hepatitis C is pegylated interferon-α (PEG-IFNα) and ribavirin (RBV). The treatment achieves a sustained viral clearance in only approximately 50% of patients. Recent whole genome association studies revealed that single nucleotide polymorphi...

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Detalhes bibliográficos
Main Authors: Sugiyama, Masaya, Tanaka, Yasuhito, Wakita, Takaji, Nakanishi, Makoto, Mizokami, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201970/
https://ncbi.nlm.nih.gov/pubmed/22046316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026620
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